

MK International Medical - Japanese high-class cell therapy services

MK International Medical - Japanese high-class cell therapy services

Immune Cell Therapy
Cancer treatment and prevention without side effects
What is immune cell therapy?
White blood cells consist of neutrophils, lymphocytes, monocytes, basophils, and eosinophils, and eliminate foreign pathogens (i.e., bacteria and viruses) and transformed cells (i.e., cancer cells) in your body.
And within white blood cells, natural killer cells (also known as NK cells) are a population of lymphocytes that promptly attack and eliminate cancer cells and virus-infected cells.
Our immune cell therapy is that expanding NK cells and activate by cell culture, and administered to you for the prevention or treatment of cancer as well as viral infection.
When is it appropriate to do immune cell therapy?
・Healthy People: To preventing cancer and viral infections
・With surgery and proton therapy: preventing cancer recurrence
・With chemo and monoclonal antibodies: synergistic effect
・Palliative care: delay progression, improve quality of life, and improve prognosisCancer Immune Cell Therapy
Doctor will make a personalized treatment plan according to your condition, please contact us for details.
NK Cell Therapy
NK cell therapy is a treatment in which the patient's NK cells are activated and cultured in large quantities at a cell culture facility certified by the Ministry of Health, Labour and Welfare of Japan, and then infused into the patient's body in order to destroy the cancer cells. Since using autologous cells, there are almost no side effects.
In addition to NK cells, we also proliferate αβ T cells, γδ T cells, NKT cells and other immune cells to maximize the immune system's ability to fight cancer.
Dendritic Cell Therapy
Dendritic cells (DC), which are antigen-presenting cells, are like commanders of an army. When NK cells destroy cancer cells, dendritic cells will uptake the antigens of the cancer cells and educate T lymphocytes of specific immunity to attack the cancer cells.
The culture facility will use the monocytes collected by apheresis and use CEA/WT-1/VEGF vaccine according to the disease condition to stimulate the monocytes to differentiate into dendritic cells. After culturing, dendritic cells will be administered by infusion or subcutaneous injection to the lymph nodes.
Immunology Test
We will do immunology tests, general blood tests, tumor marker tests before and after the treatment to compare the values and evaluate the effect of the treatment.
※Depending on the severity of the condition and personal constitution, the improvement might be different, the doctor will explain about the results.
Procedure of Cancer Immune Cell Therapy
1Consultation
First of all, please contact us to fill out the consultation form and provide us with the examination information. We will discuss your condition with physician and make a treatment plan based on the type of cancer, your condition and progression.
We can also assist in arranging an online consultation if required.
2Apheresis
After consultation with physician, we will perform the blood collection required for cell culture. For cancer patients, we use apheresis(blood component collection) to collect large quantities of lymphocytes.
We will deliver the samples to the cell processing facility for culturing after apheresis.
3Cell Culturing
The blood samples will be cultured at a cell processing facility certified by the Ministry of Health, Labor and Welfare. Immune cells can be infused after 2 weeks of culturing.
In order to provide the safest regenerative medicine services to all clients, all cells cultured at the facility undergo comprehensive quality control and safety testing upon completion of culture.
※You can choose to stay in Japan or return to your country during culturing period.
4Treatments
You will have an intravenous infusion of immune cells at the clinic. Cancer patients will receive intensive infusions of immune cells within 8-10 days. The infusion takes about 30 minutes to 1 hour.
※If you wish to have another treatment, you can do an apheresis again during your treatment in order to collect the cells for the next treatment.
Cancer Prevention for Healthy People
Preventing Cancer by Using NK Cells to Destroy Invisible Cancer Cells
Did you know that cancer cells are produced in our body every day?
Studies have shown that even healthy people produce more than 5,000 cancer cells every day.
But because our immune cells patrol the body and attack these cancer cells, we can continue to live healthy lives without cancer.
Do you know your NK cell activity?
NK cell activity is the ability of NK cells to kill cancer cells within a certain period of time. However, aging, lifestyle habits and stress can reduce the activity of NK cells and therefore their ability to resist cancer and viral infections.
※Your NK activity can be tested at the clinic.
What is the effect of low NK activity?
NK cells are like security guards in our body. Once NK cells find abnormal cells such as cancer cells, NK cells will destroy these abnormal cells immediately. However, once the activity (attacking ability) of NK cells decreases and cannot keep up with the growth of cancer cells, then we are at risk of developing cancer.
According to a tracking survey conducted in Saitama Prefecture, Japan, the cancer rate of people with low NK activity was 70% higher than that of people with high activity.
When you're healthy, it's hard to imagine getting cancer, but nowadays, one in two people have cancer. Cancer treatment is very painful, so the best way is to get rid of undetectable cancer cells before the cancer develops. Immune cell therapy can effectively improve immunity and reduce the risk of cancer.
Procedure of Immune Cell Therapy for Healthy People
1Consultation
First of all, please contact us to fill out the consultation form and provide the examination information, we will discuss with the doctor and decide the treatment plan according to your needs and physical condition.
We can also assist in arranging an online consultation if required.
2Blood Withdrawal
After consultation with physician, we will perform the blood collection required for cell culture. For healthy people, we will take 50cc of whole blood for immune cell culture.
We will deliver the samples to the cell processing facility for culturing after blood withdrawal.
3Cell Culturing
The blood samples will be cultured at a cell processing facility certified by the Ministry of Health, Labor and Welfare. For healthy people, the infusion can be started after 3 weeks of culturing.
In order to provide the safest regenerative medicine services to all clients, all cells cultured at the facility undergo comprehensive quality control and safety testing upon completion of culture.
※You can choose to stay in Japan or return to your country during culturing period.
4Treatment
You will have an intravenous infusion of immune cells at the clinic. If you wish to continue treatment in the future, we will withdraw the blood for the next treatment while infusion.
The infusion takes about 30 minutes to 1 hour.
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